Abstract. Elderly patients are characterized by the presence of several diseases at once(polymorbidity). This is due to the simultaneous appointmentof severaldrugs (polypharmacy) to such patients. But at the same time, polypharmacy reduces the effectiveness of treatment and increasesthe risk of adverse reactions. Therefore, it is extremely important to select drugs individually in compliance with the indications and contraindications for their appointment, to take into account the interaction of drugs and the possibility of the drug's influence on concomitant pathology, to use only proven effectiveness and safety drugs, to guide by Beer's criteria, to unexceed the recommended doses, to include in complex therapy metabolic drugs to optimize elderly patients drug therapy
Conclusion Thus, to optimize the elderly patient drug therapy, it is necessary to individually select drugs in compliance with the indications and contraindications for their appointment; take into account the drug interaction and the possibility of the drug influence on concomitant pathology; use only proven effectiveness and safety drugs; do not exceed recommended doses; do not prescribe unrecommended drugs for use in geriatrics, include metabolic drugs in complex therapy. Adherence to these principles will ensure drug therapy effectiveness and safety for elderly patients. Author Contributions: All authors participated equally in writing this article. Conflicts of Interest: The authors declare no conflict of interest. 18
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